Patients with metastatic melanoma that had relapsed on anti-PD-1 therapies or BRAF/MEK inhibitors did not respond as well to an investigational therapy that involves the adoptive cell transfer of ...
Patients with high-grade serous ovarian cancer (HGSOC) are prone to relapse and low survival rates following current best treatment strategies. Engineered chimeric antigen receptor (CAR) T cells have ...
In vitro expansion of CMV-specific CD4+ T-cells by artificial antigen presentation for adoptive immunotherapy in the post- transplant setting No significant financial relationships to disclose. This ...
Intravenous administration of ALKS 4230 as monotherapy and in combination with pembrolizumab in a phase I study of patients with advanced solid tumors. The "INSIGHT" Trial: Two new strata of an ...
Understanding the mechanism by which tolerance is induced is essential to developing new approaches to induce tolerance in clinical transplantation. A new study reports the successful induction of ...
T cells engineered to express chimeric antigen receptors (CARs) or engineered T-cell receptors (TCRs) have enabled a new generation of targeted cellular therapeutics. Philip Greenberg, MD, an ...
Adoptive T cell therapy is a type of immunotherapy that has the ability to target cancer cells through inherent mechanisms of the immune system. The method works by infusing tumor-specific cytotoxic T ...
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