Nature

Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function

The C. elegans SAX-3/Robo receptor acts in anterior–posterior, dorsal–ventral and midline guidance decisions. Here we show that SAX-3 signaling involves the C. elegans Enabled protein UNC-34 and an ...
Nature

A Commentary on Axon guidance pathway genes and Parkinson’s disease

Axon guidance pathway is one of the critical processes related to connectivity and repair of the wiring of the brain during the central nervous system development and throughout the lifetime in humans ...
Medical Xpress

Researchers reveal signaling mechanism for proper guidance of developing axons

An international team of scientists led by Université de Montréal medical professor Frédéric Charron, director of the molecular biology of neuronal development research unit of the UdeM-affiliated ...
ascopubs.org

Expression of the axon guidance protein Robo1 in pancreatic ductal adenocarcinoma from smokers compared to nonsmokers.

ING3 as a novel regulator of pancreatic cancer growth and aggressiveness. Coagulation factors in citrated plasma predict for benefit from bevacizumab (B) in patients with advanced pancreatic cancer ...
Yale Environment 360

Gruber Neuroscience Prize awarded to three for their work on axon guidance

The 2020 Gruber Neuroscience Prize is being awarded to three neuroscientists — Friedrich Bonhoeffer, of the Max Planck Institute for Developmental Biology; Corey Goodman, of venBio; and Marc ...