Alzheimer's dementia is caused by accumulation of amyloid-β protein in neurons, formed from proteolytisis of amyloid precursor protein (APP), but the normal role of APP in the brain remains unclear.

RNA granules, sites for the storage, transport, and regulation of RNA molecules within cells, are transported along axons and then translated locally, far from the cell body. Recent studies suggest ...

Neurons, specialized cells that transmit information across the nervous system, communicate with each other via projections known as axons. These microscopic, cable-like structures are also used to ...

Seeking students to contribute to research exploring motor-disease protein complexes and their role in intracellular transport, as they relate to disease initiation and the aging process, and the ...

Huntington's disease is a genetic neurodegenerative disorder caused by mutations in the protein huntingtin and characterized by involuntary dance-like movements, severe behavioural changes and ...