Basement membranes are extracellular matrices—flat sheets of protein and carbohydrate—that are essential for tissue architecture and function. But like all tissues, they are subject to damage. Until ...

Studies by scientists at Massachusetts Institute of Technology (MIT), Beijing Normal University, and the University of California, San Diego (UCSD) have generated new insights into the elastic ...

Researchers report that they have evidence of a coordinated attack on the basement membrane of human colon cells by cancer cells in situ and CAF cells in the extracellular matrix that begins long ...

Scientists have exposed a cell pathway that breast tumor cells use to destruct local tissue neighborhood. Cancer cells may use this pathway to free themselves from mammary epithelial tissue ...

Ultrastructural studies of centipede and other myriapod ovaries reveal direct soma-germline contact across the basement membrane, a structure typically regarded as a cellular barrier. A new study by ...

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable. But once these cancers become invasive – breaking through a thin matrix around ...

Scientists at Duke University say they made the first time-lapse movies of the sheet-like latticework that surrounds and supports most animal tissues. A thin layer of extracellular matrix known as the ...

In 2020, right when Jane Baude was starting her Ph.D. research at UC Santa Barbara, she learned that a critical component of her experiment — the gel needed to grow and test mammary epithelial cells — ...

The foot bone’s connected to the leg bone, the leg bone’s connected to the knee bone — thanks in part to a newly discovered chemical bond, researchers report in the Sept. 4 Science. The bond — never ...