Alzheimer's disease (AD) is the most common form of dementia in the aging population. Although the precise molecular precursors of AD remain elusive, the majority of evidence indicates that β-amyloid ...

We compare here the neurodegenerative processes observed in the hippocampus of bitransgenic mice with chronically altered levels of cAMP-response element-binding protein (CREB) function. The ...

Study shows that that pace at which a brain cell activates a key protein may influence its role in memory formation—a finding that could lead to new Alzheimer therapies Remember the old myth that ...

Scientists know that the ravages of Alzheimer disease cripple the ability to lay down new memories, but the precise molecular dance that determines the success or failure of memory formation is still ...

The expression of a gene called CREB in certain neurons may function as a switch to regulate feelings of fear and its extinction. Targeting this gene may provide new information and treatments for ...