Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases. This ...

Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking. A new ...

New approach for anti-RSV compound discovery. The respiratory syncytial virus (RSV) has been identified as a major causative agent of bronchiolitis in children; nevertheless, avai ...

Using robots and click chemistry, scientists built potential active ingredients for future antibiotics that contain metal.

Scientists have identified lucidenic acid A, one of the bioactive compounds of Ganoderma lucidum, as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) host cell ...

Clinical failure in the pharmaceutical industry remains at a staggering 90%. Failed drugs are costly, both financially and in terms of human suffering. The debate rages on about how best to fix the ...

Nuclear receptors are popular targets for drug companies searching for new therapeutics for cancer and cardiovascular, metabolic, inflammatory, and other diseases. Indigo Biosciences in State College, ...

Drug screening is a key step in early drug discovery, and researchers are constantly working to strike the right balance between biological relevance and experimental efficiency. While high-throughput ...