The interplay between contractility and mechanosensing in striated muscle is important for tissue morphogenesis, load adaptation, and disease progression, but remains poorly understood. Here, we ...

Skeletal muscle sodium channel disorders give rise to episodic symptoms such as myotonia and/or periodic paralysis. Chronic symptoms with permanent weakness are not considered characteristic of the ...

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice. The mutation was found to ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Cytokinetics Inc. has identified bicyclic piperazinones with the ability to modulate skeletal muscle contractility reported to be useful for the treatment of amyotrophic lateral sclerosis, spinal ...

The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a University of Michigan study. Nearly all animals use muscle to move, and it's been known for a long ...

Accelerating Drug Discovery with Human-Relevant 3D Engineered Muscle Tissue Analysis SEATTLE--(BUSINESS WIRE)--Curi Bio, a leading developer of human stem cell-based platforms for drug discovery, ...

In a recent study published in Reviews in Medical Virology, researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long coronavirus disease ...

The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study. The flow of water within a muscle fiber may dictate how quickly muscle can contract, ...

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice. The mutation was found to ...