DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...
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DNA shape and stiffness steer key gene regulators
For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new wave of research is forcing a rethink, showing that the three-dimensional ...
Researchers found how the INO80 protein moves nucleosomes to specific positions that are important for gene regulation and DNA replication INO80 uses a unique mechanism for moving nucleosomes that ...
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