Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

How do cells turn into organs? During embryonic development, three germ layers form, known as the endoderm, the mesoderm, and the ectoderm. These germ layers give rise to different parts of the ...

Advances in genetic and computational tools have enabled researchers to study complex networks of gene expression in individual cells, and the patterns of gene expression in a population of cells ...

Huntington’s disease (HD) was the first neurological disorder to be linked to a mutation in a single gene—a discovery made more than 25 years ago. However, neither the pathogenic mechanisms leading to ...

At the earliest stages of human embryonic development, a small collection of cells known as human embryonic stem cells (hESCs) orchestrates growth and differentiation, eventually giving rise to highly ...

By engineering a system replicating the womb lining with high biological accuracy, researchers at the Babraham Institute and ...

A new study from the MRC Laboratory of Medical Sciences (LMS) in London, UK reveals how ancient viral DNA once written off as ...

One of the biggest quests in biology is understanding how every cell in an animal's body carries an identical genome yet ...

Gene networks in human embryonic stem cells (hESCs) have been found to serve two purposes at once. They maintain pluripotency, and they keep apoptosis, or programmed cell death, on a hair trigger.