Rhobo6, a light microscopy probe, gives scientists an unprecedented look at the extracellular matrix -- the collection of organized molecular structures that fills the spaces between cells in our ...

Senescence. It’s a beautiful-sounding word whose tones suggest it should be a perfume or an essential oil. But that’s not ...

Structural alignment in fibrous tissues like myocardium and tendons is a key biomarker of physiological integrity and ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate a novel approach for nanoscopic profiling of small extracellular vesicles (sEVs) using high-speed atomic ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered a specialized population of neutrophils in the skin that produce extracellular matrix components, helping ...

A recent study published in the Journal of Extracellular Vesicles explored how high-speed atomic force microscopy (HS-AFM) videography can be used to analyze small extracellular vesicles (sEVs) at the ...

All cells, from bacteria to mammalian cells, produce extracellular vesicles—tiny membrane-enclosed packages of bioactive cargo. 1 Until relatively recently, scientists believed these organic ...

The field of tissue engineering aims to repair and regenerate damaged organs or tissues using ex vivo tissue constructs. A key challenge lies in the design and fabrication of scaffolds that facilitate ...

Fascia of live mouse pancreas, in which the extracellular matrix is labeled with Rhobo6 (red) and nuclei are labeled with Hoechst (cyan). Maximum intensity projection shown. Before arriving at Janelia ...