The framework predicts how proteins will function with several interacting mutations and finds combinations that work well together.

Large-scale protein and gene profiling have massively expanded the landscape of cancer-associated proteins and gene mutations, but it has been difficult to discern whether they play an active role in ...

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for scientists to study their individual units without altering their natural structure.

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.