Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

New research suggests that alternative splicing may have an even greater influence on biology than just by creating new protein isoforms. The study shows that the biggest impact of alternative ...

New method ASPEN accurately maps gene activity from each parent in individual cells, overcoming noise in data. It revealed ...

This breakthrough allows researchers to visualize where individual genes are active at the cellular level—information that has long been missing due to technical limitations in tea biology. By ...

A new Yale study provides a fuller picture of the genetic changes that shaped the evolution of the human brain, and how the process differed from the evolution of chimpanzees. For the study, published ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Precision Treatment of Patients With GI Cancer Using Pre-emptive DPYD Genotyping/Phenotyping Plus Pharmacokinetic-Guided Dosing of 5-Fluorouracil Primary PCa biopsy samples underwent ...

Researchers have identified specific coupled patterns of brain activity and gene expression that help explain impulsive behavior in children with attention deficit hyperactivity disorder. By analyzing ...

A shared molecular signature of Alzheimer’s appears across populations once studied in isolation. Alzheimer's disease (AD) affects African Americans (AA) at roughly twice the rate seen among ...