Using sequencing instruments from multiple vendors, scientists from the University of Utah Health, the University of Washington, PacBio, and elsewhere have developed what they claim is the most ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

The analysis revealed that about 2 per cent of sperm from men in their early 30s contained disease-causing mutations. That figure rose to between 3 and 5 per cent in middle-aged men (43 to 58 years) ...

The illustration of protein structure (domains) on the left side, and corresponding exons in the FLT3 gene are displayed on the right side. FMS-like tyrosine kinase 3 (FLT3) mutations represent some ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

High-accuracy single-molecule unique molecular identifier sequencing reveals non-random, biologically driven mutation heterogeneity within influenza quasi-species, enabling precise profiling of ...

Lung cancer remains the leading cause of cancer-related deaths globally, with cigarette smoking as its primary driver. Chemical carcinogens like polycyclic aromatic hydrocarbons (PAHs) in tobacco ...

Lung cancer remains the world’s deadliest cancer, and cigarette smoke is its chief culprit. Chemicals in tobacco, such as polycyclic aromatic hydrocarbons (PAHs), damage DNA and trigger the mutations ...