The symptoms of neurodegenerative diseases like Alzheimer’s, frontotemporal dementia, and chronic traumatic encephalopathy (CTE) are different, but they have one feature in common: the presence of ...

(A, B) Neurons are specialized eukaryotic cells that extend long processes to form connections in the nervous system. Like other eukaryotic cells, neurons have a cytoskeleton that consists of three ...

Just as the skeleton and muscles move the human body and hold its shape, the cells of the body are stabilized and moved by a cellular skeleton. This cellular skeleton is a dynamic structure, ...

Low complexity (LC) head domains 92 and 108 residues in length are, respectively, required for assembly of neurofilament light (NFL) and desmin intermediate filaments (IFs). As studied in isolation, ...

Neurofilament light (NfL) is a 68 kDa cytoskeletal intermediate filament protein highly expressed in neuronal axons. It is associated with the 125 kDa Neurofilament medium (NfM) and the 200 kDa ...