Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

Human organoids are 3D cell cultures derived from adult stem cells and maintain the variable distribution of epithelial cells seen in primary tissue. They can recapitulate the mechanisms of epithelial ...

A cell model that replicates the structure and function of the human intestine has been developed, creating an evaluation platform capable of more accurately predicting adverse effects of new drugs.

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

Miniature organs grown in the lab can organize themselves into complex shapes. But they never do it the same way twice, which makes it hard to use these so-called "organoids" to study disease. Now, ...

In a recent study published in the journal Frontiers in Immunology, researchers investigate the impact of dietary antigens in regulating small intestinal tumors. Despite being the most common type of ...

Silica nanoparticles may make oral insulin possible by safely enhancing drug absorption through the intestinal wall in obese mice.

Animal models have enabled us to learn an incredible amount of new information about human biology, health, and disease. But these animals can't always serve as a reliable example of the human body.

The human small intestine is an essential organ that helps us absorb nutrients and vitamins from food. It is an average of 6 meters long and is covered with millions of villi that are separated by ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...