Lymph nodes, hundreds of small structures located throughout the body, play a pivotal role in immunity, including anti-tumor immune responses. White blood cells, also known as lymphocytes, reside in ...

Tumors, such as melanoma, release nanovesicles called exosomes (gray) that travel and lodge in the lymph nodes. There they corrupt the behavior of lymph cells. The lymphatic vessels (green) branch out ...

New research shows lymph nodes aren’t just cancer bystanders, they’re the command centers fueling immune attacks. Surgically removing them along with tumors may weaken treatment, while preserving them ...

Researchers have developed a new nanoparticle that can 'hitch a ride' on immune cells, or monocytes. Because of its tiny size, the particle can tag along directly into lymph nodes and help metastasis ...

These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

Safety, tolerance, and preliminary efficacy of autologous tumor-infiltrating lymphocytes (TILs) LM103 injection in Chinese patients with advanced melanoma and an exploration of the factors influencing ...

For years, it has been a mainstay of treatment to stop the spread of many cancers. But is the removal of lymph nodes – tiny, bean-shaped nodules that filter waste and bacteria – really the best way to ...

Structure of a lymph node (IMAGE) Centro Nacional de Investigaciones Oncológicas (CNIO) Caption Structure of a lymph node whose endothelial cells (green) are capturing the nanovesicles called exosomes ...