Epigenetics, the modification of chromosomes without altering DNA sequences, serves as a crucial regulatory mechanism for gene expression. Among the various epigenetic marks, N6-methyladenosine (m6A) ...

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs). As the most abundant internal modification of ...

Image Caption: The molecular mechanism of m6A methylation. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular ...

Duke researchers published a breakthrough in understanding m6A through the development of a genetically encoded sensor for the most abundant internal mRNA modification. These mRNA modifications are ...

Immunologists have revealed the essential function of m6A modifications in T cells. The research group working with immunologists Vigo Heissmeyer and Taku Ito-Kureha of LMU and Helmholtz Munich has ...

Association of body mass index change and insulin resistance with survival during induction therapy in newly diagnosed multiple myeloma.

m6A RNA modifications could explain why females have a higher liver fat content than males, with gene therapy being a potential treatment option for liver disease. Non-alcoholic fatty liver can lead ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...