Combined epigenetic and immune checkpoint therapy altered the tumour microenvironment in platinum-resistant ovarian cancer.

This infographic explores the core components of the TME, their roles in cancer progression and how they can be leveraged to ...

Throughout the entire process of cancer aetiology, progression and metastasis, the microenvironment of the local host tissue can be an active participant. Invasion occurs within a tumour–host ...

An interdisciplinary multi-centre research team led by the LKS Faculty of Medicine (HKUMed) and Faculty of Dentistry at the ...

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

An interdisciplinary multi-center research team led by the LKS Faculty of Medicine (HKUMed) and Faculty of Dentistry at the University of Hong Kong has constructed the world's largest multi-omics ...

Targeted cancer drugs known as CDK4/6 inhibitors have improved outcomes for patients with advanced or metastatic HR+/HER2- breast cancer, but many patients still eventually relapse and become ...

The tumor microenvironment is a battleground where infiltrating immune cells either subdue or promote a cancer, all while cancer cells try to dampen the body’s defenses. 1,2 Scientists have studied ...

SOX30-mediated activation of CXCL2 as promotor of PMN-MDSC recruitment and immunosuppressive microenvironment in TNBC. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

A silicon-based nanothrombolytic combines clot dissolution with local microenvironment regulation, enhancing safety and efficacy in thrombotic disorders.