Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as pivotal players, offering new avenues for understanding the fine-tuned ...

Lockdowns may have exacerbated immune responses in PLHIV due to changes in inflammatory regulation and lifestyle alterations. Significant immune profile differences were observed pre- and ...

CARs, chimeric antigen receptors; CD, cluster of differentiation; CTLA-4, cytotoxic T-lymphocyte-associated protein 4; IL, interleukin; NK, natural killer; PD1 ...

On the one hand, circadian rhythm disorder contributes to tumor growth and metastasis by influencing the dysregulation of gene expression affecting the tumor itself. On the other hand, circadian ...

Survival in ER-positive/HER2-negative non-metastatic invasive breast cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does ...

Cancer immunotherapy has transformed the treatment landscape for multiple malignancies; however, its clinical efficacy remains limited in many tumors due to ...

Enhancing tumor microenvironment composition to favor PD-1 inhibition via pretreatment with low-dose per fraction radiotherapy in a mouse breast cancer model. This is an ASCO Meeting Abstract from the ...

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...