The world has changed since 1664, when French philosopher and scientist Rene Descartes first claimed the brain was responsible for the sensation of pain. However, a key question remains: How exactly ...

Pain represents the cardinal symptom of osteoarthritis, yet its intensity, quality, and impact vary dramatically among ...

Chronic pain is a multifaceted condition that extends beyond the typical duration of an acute injury and involves complex neurophysiological processes. Today’s understanding of chronic pain ...

A study has uncovered new insights into how the brain processes and integrates pain information. The research goes beyond identifying brain areas that respond to pain, revealing the mechanisms behind ...

Researchers show that inhibitory interneurons, which prevent chemical messages from passing between different regions of the brain, make up 20% of the circuitry in the brain required for pain ...

A new University College London study reveals that a newborn's response to pain is more complex and less conscious than previously thought. Researchers have discovered that while premature babies can ...

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

Feeling like we have a degree of control makes us tolerate pain better. In the case of fibromyalgia, however, this simply doesn’t work. A study provides clues as to why. The degree to which we ...

Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...