Cell development, proliferation and death form a tightly interwoven continuum that underpins both normal physiology and disease. At its core, the orchestration of the cell cycle ensures that cells ...
In an extensive review, researchers explore ZBP1-mediated programmed cell death and its potential as a therapeutic target for systemic diseases Programmed cell death, or PCD, is an actively regulated ...
A team of researchers at the University of Cologne’s Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...
Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate ...
Selective ASO-based JAK2 inhibitor for the treatment of hematological malignancies with JAK2 V617F mutation burden. Use of causal modeling to uncover cell-cell communication dynamics in the tumor ...
In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.
Discover the challenges of acute myeloid leukaemia linked to inflammatory cell death and the quest for effective therapies.
This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...
US pharma major AbbVie and China’s RemeGen today announced an exclusive licensing agreement for the development, ...
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