Proteomics and genomics share the common goal of characterizing biological systems, yet they differ fundamentally in their molecular targets, analytical challenges and interpretive value. Genomics ...
Expert Rev Proteomics. 2009;6(4):421-431. Thus far, many groups have been working in the study of serum protein changes during the development of liver fibrosis. [54–58] It was of great clinical ...
Data independent analysis and hyper reaction monitoring have recently emerged as new methods of mass spectrometry which address some of the shortcomings of traditional procedures. This review ...
Large-scale protein and gene profiling have massively expanded the landscape of cancer-associated proteins and gene mutations, but it has been difficult to discern whether they play an active role in ...
The first-in-human phase 1/2 study of TSN1611, a highly selective KRAS G12D inhibitor, in patients with advanced solid tumors. Seizure-related homolog 6 (SEZ6) expression and ctDNA methylation ...
Membrane proteins are the gateway to cells and are involved in many critical functions. Each membrane protein is unique, and their complexity makes it difficult to fit into a standardized expression ...
Making proteins for research or therapies often starts with cell-line development. In many applications, genetic engineering is used to optimize a cell line for producing high levels of the intended ...
Comprehensive Genomic Assessment of Advanced-Stage GI Stromal Tumors Using the Japanese National Center for Cancer Genomics and Advanced Therapeutics Database We analyzed the genomic and immune ...
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