Patients with inflammatory bowel disease and pyoderma gangrenosum or erythema nodosum displayed distinct clinical and genetic characteristics that may indicate shared etiologies in a recent study.

Background A 20-year-old female presented to her gastroenterologist with fevers and right-labial pain and swelling. Painful erythematous nodules developed in her pretibial region soon after admission ...

Pyoderma gangrenosum was first described as an extraintestinal manifestation of inflammatory bowel disease (IBD) by Brunsting and colleagues in 1930. 1 They described painful enlarging necrotic ulcers ...