A new Northwestern Medicine study has revealed how a common inherited mutation disrupts red blood cell development and sparks inflammation that can lead to leukemia, according to findings published in ...

Co-corresponding authors Jian Xu,PhD, (left) and Min Ni, PhD, (right) and co-first authors Junhua Lyu, PhD, (center left) and Yuannyu Zhang, PhD, (center right) identified and characterized a ...

It is well known that type 2 diabetes raises the risk of heart attack and stroke and that risk tends to increase over time. A new study from Karolinska Institutet suggests one possible reason may sit ...

The amino acid glutamine plays an unexpected role in erythropoiesis, the differentiation of erythroid progenitor cells into mature red blood cells. Ordinarily, glutamine is broken down by stem cells ...

The production of red blood cells from stem cells has emerged as a transformative approach to address chronic blood shortages and meet the increasing demand for transfusion therapies. By harnessing ...

A selective protein degradation system known as Golgi membrane-associated degradation (GOMED), which identifies and removes ...

In their quest for safe, mass-producible artificial blood, geneticists have long struggled. Our limited knowledge of genetic pathways that govern the development of blood has kept us from producing ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...