Recent neuroscience studies have consistently outlined the role of the C9ORF72 gene in the development of some neurodegenerative diseases. These studies found that mutations of this gene increase the ...
RNA clusters (green colored) gradually disassemble within biomolecular condensates (magenta colored), returning the RNA to a soluble state. This occured after an antisense oligonucleotide engineered ...
Look inside a brain cell with Huntington’s disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...
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