Central sensitization syndrome can cause the brain to overreact to harmless stimulation, leading to intense pain feelings. Typically, the CNS sends sensory signals to the brain. The brain accurately ...

The incidence of chronic pain is estimated to be 20–25% worldwide. Few patients with chronic pain obtain complete relief from the drugs that are currently available, and more than half report ...

Although David Segal has sadly passed away, he leaves as one legacy to those who were fortunate to have had the opportunity to know and admire him, an enduring interest in the paradox of behavioral ...

Pain represents the cardinal symptom of osteoarthritis, yet its intensity, quality, and impact vary dramatically among ...

Peripheral sensitization refers to the lowering of the threshold of excitability of sensory neurons, which leads to an amplified reaction to a specific external stimulus. Sensitization can be mediated ...

The burden of chronic pain. Source: GoodIdeas / Shutterstock Nerve sensitization often contributes to chronic pain states, such as back pain, migraines, and irritable bowel. Sensitization is an ...

A research team performed a large-scale genome analysis of Japanese and European populations and discovered gene regions (genetic polymorphisms) related to allergic sensitization. Some of these ...

NEW YORK--(BUSINESS WIRE)--The International Collaboration on Cosmetics Safety (ICCS) announces its first-ever Best Practice Guidance (BPG): “Skin Sensitization Assessment: Using New Approach Methods ...

Panel A shows initial lesions of early-onset atopic dermatitis involving the cheek and scalp in an infant at 4 months of age. Panel B shows classic head and neck manifestations of atopic dermatitis in ...

In the modern socio-economic landscape, the pursuit of equity stands as a cornerstone for sustainable development and societal harmony. As communities become increasingly diverse, the need for ...