Jia’s team developed a protocol to improve the screening of protein pockets. This involved identifying the pockets, removing ...

This article and associated images are based on a poster originally authored by Adam Buckle, Julia Unsicker and Iain McWilliam and presented at ELRIG Drug Discovery 2025 in affiliation with Arrayjet ...

MPA-CF 3 specifically binds to COPZ1, a subunit of COPI. Upon binding, MPA-CF 3 destabilizes COPZ1 and disrupts the interaction of COPZ1 with the EV-A71 2C protein in a concentration-dependent manner.

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics. There are only eight approved small ...