Tranexamic acid (TXA) failed to reduce the need for red blood cell (RBC) transfusion following surgery for liver cancer, including colorectal liver metastases, the placebo-controlled HeLiX trial ...

Use of tranexamic acid (TXA) reduced the risk of major bleeding in patients undergoing urologic surgery, results from the randomized POISE-3 trial showed. Among more than 1,100 patients, 6.1% of those ...

A drug developed as an antidote to the antiplatelet agent ticagrelor safely and effectively reversed ticagrelor's antiplatelet effects in patients undergoing urgent surgery or experiencing major ...

Little is known about the risk of bleeding in patients with bleeding disorders who undergo major surgeries or outcomes for those managed perioperatively at hemophilia treatment centers. With ...

Research from North Carolina State University found an injectable particle could help reduce blood loss in infants during ...

Postoperative bleeding is one of the most common complications after cardiac surgeries, especially in open heart ones. In this kind of surgery, surgeons need to resort to cardiopulmonary bypass, an ...

Biomedical researchers have designed an injectable microgel to help reduce bleeding in infants who require surgical care. In an animal model, the engineered microgel reduced bleeding by at least 50%.

In patients experiencing excessive bleeding during cardiac surgery, a concentrated blood product containing proteins that help the blood clot was significantly more effective and caused fewer adverse ...

Cryopreserved platelets with a 2-year shelf life did not demonstrate noninferiority to conventional liquid-stored platelets in controlling bleeding after cardiac surgery, with the upper bound of the ...

An RCT supports tranexamic acid prophylaxis to reduce major bleeding risk requiring transfusion during urologic surgery. POISE-3 included a large, clinically relevant perioperative population that is ...