As people age, their immune function gradually declines, coinciding with increased cancer rates. However, the precise reasons behind age-related dysfunction of CD8+ T cells in cancer remain unclear.

Non-cardiotoxic anthracycline demonstrates activity where traditional chemotherapies have historically failed, supporting potential expansion of ...

"Using 2 complementary methods, we demonstrated that T cells in the lung tumor microenvironment do, in fact, demonstrate evidence of poor immune function." — Brinda Emu, MD, Yale University School of ...

For decades, cancer immunotherapy has focused primarily on CD8 + cytotoxic T lymphocytes as the main executors of tumor cell killing. However, growing clinical and single-cell sequencing evidence ...

A new UCLA Health Jonsson Comprehensive Cancer Center study suggests that the way immune cells are organized inside melanoma ...

Cytokines contribute to the antitumor response through several key pathways and interactions with different immune cells. These include the following: (a) Natural killer (NK) cells: Cytokines such as ...

a complete cycle of natural lactation (21 days) followed by weaning, with tissue analyzed at 28 days after involution when the mammary gland had returned to a pre-pregnancy state (d28-inv mice) early ...

Jianmei Leavenworth, M.D., Ph.D., associate professor in the Department of Neurosurgery, has been named the latest recipient of the school’s Fea Jianmei Leavenworth, M.D., Ph.D.tured Discovery award.