Alcoholics should avoid excessive physical and psychological stress during early abstinence. The hypothalamic-pituitary-adrenal (HPA) axis defends against stress, starvation and illnesses. A new study ...

We investigated the effect of chronic nicotine self-administration (SA) on hypothalamic–pituitary–adrenal (HPA) hormonal responses to acute stressors. Adult male Sprague–Dawley rats were given access ...

Corticosteroid therapy must be tapered because of its interactions with the hypothalamic-pituitary-adrenocortical (HPA) axis. The hypothalamus secretes corticotropin releasing factor, which acts on ...

A study of individuals with treatment-resistant depression found that hormones associated with the hypothalamic-pituitary-adrenal (HPA) axis do not influence the antidepressant effects of ketamine.

H. Lundbeck A/S (Lundbeck) today announced preliminary Phase II Part A data from its ongoing study evaluating asedebart (Lu AG13909), an anti-adrenocorticotropic hormone (ACTH) monoclonal antibody, in ...

Adrenocorticotropic hormone (ACTH) is a hormone that the pituitary gland produces. Its main function is to stimulate the adrenal glands to produce and secrete another hormone called cortisol. Some ...